CXCR2 and neoplasm: Acrolein stimulated cell migration of Müller glial cells through induction of C-X-C motif chemokine ligand 1 (CXCL1) protein (65), a member of the C-X-C family of chemokines that promotes neutrophil and tumor cell migration through binding to the receptor C-X-C motif chemokine receptor 2 (CXCR2) (69, 70).