HSP90B2P and Behcet disease: The hyper-reactivity against Streptococcus sanguinis antigens and the homology and potential cross-reactivity of some of its proteins with human heat-shock proteins (HSP) (30), as exemplified by the activation of T γδ+ cells by the pathogen and HSP 60/65 kDa (31), suggest this infectious agent might play an important role in BD pathogenesis (32).