Haerynck et al. (86) found an association of the A variant [related to MASP1 gene +1851 G>A (rs3821805) SNP, localized in exon 12, encoding for MASP-3 SP domain) with earlier onset of chronic Ps. aeruginosa colonization in cystic fibrosis patients. This evidence concerns the gene MASP1 and cystic fibrosis.