In contrast to Yellow Fever vaccination, vaccination with Trivalent inactivated influenza Vaccine (TIV) did not induce an increase in JAK-STAT1/2 or JAK-STAT3 pathway activity scores in PBMCs within the same time frame (one week) after vaccination, suggesting that this vaccination had not induced full immunity (Figures 6E, F). The gene discussed is STAT1; the disease is influenza.