Likewise, phosphorylation of STAT1 and STAT2 in 16HBE cells pre-treated with IL-36γ was mildly inhibited at 12 h after IAV-Ca07 infection, while no significant changes in Mx1, PKR, IAV-Ca07 NP, and M1 protein were observed (Figure 6E). The gene discussed is STAT1; the disease is infection.