Similarly, MPs isolated from SSc patients with lung fibrosis showed a greater profibrotic profile, with an upward trend for Col1a1/MMP1 (median of 1.59 vs. 0.65, p=0.1, Figure 4D) and Col1a2/MMP1 ratio (median of 2.42 vs. 0.91, p=0.07, Figure 4E), but reduced ability to induce CCL2 (median of 0.89 vs. 1.51, p<0.05, Figure 4F). Here, CCL2 is linked to systemic sclerosis.