MMP1 (mean ± sem of fold change for 10 MPs/μl: 1.25 ± 0.05; for 100 MPs/μl: 1.41 ± 0.05; for 1,000 MPs/μl: 0.92 ± 0.19, Figure 3C) and CCL2 expression (mean ± sem of fold change for 10 MPs/μl: 0.80 ± 0.01; for 100 MPs/μl: 0.78 ± 0.08; for 1,000 MPs/μl: 1.23 ± 0.08, Figure 3D), as with HD MPs, were not affected by SSc MPs. The gene discussed is MMP1; the disease is systemic sclerosis.