TNF and malignant colon neoplasm: Lactobacillus acidophilus EPS can inhibit the growth of Caco-2 colon cancer cells (Deepak et al., 2016) while EPS from L. gasseri can induce apoptosis in cervical tumor cells, also decreasing the production of TNF-α and increasing the IL-10 production thus controlling inflammation (Sungur et al., 2017).