examined PD-L1 immunoreactivity in 77 PPGL cases using an anti-PD-L1 antibody (clone E1L3N) and reported that 59.74% (46/77 cases) of PPGLs were IHC-positive for PD-L1, with high co-efficiency of Ki-67 LI, as well as the presence of hypertension (97). This evidence concerns the gene CD274 and Hypertension.