Among genes involved in fatty acid and triglycerides synthesis (Table 3), expression of the transcription factor peroxisome proliferator activated receptor gamma (Pparγ) and fatty acid synthase (Fas) decreased 3- to 4-fold (P<0.01 and P<0.001), and expression of diglyceride acyltransferase (Dgat-1) decreased slightly (P<0.01) in mice fed with WD-CA but not with WD-CDCA. The gene discussed is FAS; the disease is Wilson disease.