Although T1D individuals with complications show considerable derangement in immunological processes like having elevated concentrations of C-reactive protein (CRP), a marker of inflammation, proinflammatory cytokines interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-α) as compared to individuals without complications (9), the extent of contribution of immunological factors to the development of vascular complications in patients with T1D is poorly understood. This evidence concerns the gene CRP and type 1 diabetes mellitus.