In female SVD patients, WNK lysine deficient protein 1 (WNK1) and WNK1 mRNA-like long non-coding RNA (lncRNA; accession DQ925669) had significantly increased expression in SVD patients compared to VRFCs (Figure 2, Tables 3, 4). This evidence concerns the gene WNK1 and snowflake vitreoretinal degeneration.