SST and schizophrenia: Todd Lencz et al. (35) emphasized that the rs1344706 polymorphism in ZNF804A (a candidate gene of schizophrenia) may alter neuroanatomical (including the gyrus rectus) and neurocognitive phenotypes; besides, a post-mortem brain mRNA study has revealed that somatostatin mRNA+ cell density of the gyrus rectus layer II is lower in patients with schizophrenia than in healthy controls, which may give rise to the reduced gray matter volume (36).