GJA1 and atherosclerosis: Furthermore, Cx43 expression in monocytes also affects monocyte-endothelial adhesion (Ji et al., 2019) as inhibition of Cx43 expression in monocytes led to a decreased activity of the PI3K/AKT/NF-κB signaling pathway resulting in a decreased monocyte-endothelial adhesion, finally offering new thoughts for understanding atherosclerosis.