SFRP5 and ST Elevation Myocardial Infarction: More recently, Du et al. (2019) showed that high serum SFRP5 levels measured during the acute phase of ST segment elevation MI (STEMI) were significantly linked to early-stage myocardial recovery following primary percutaneous coronary intervention, suggesting that SFRP5 might represent a possible therapeutic target in acute STEMI.