Survey of the Gene Expression Omnibus (GEO)4 of microarray analyses identified elevation of NKLAM mRNA expression in monocytes and macrophages exposed to LPS, Borrelia burgdorferi (the spirochete responsible for Lyme disease), Chlamydia pneumoniae, Francisella tularensis (the causative agent for tularemia), Porphyromonas gingivalis (the pathogenic bacterium associated with periodontitis), M. tuberculosis, as well as upon infection with several adenoviruses and rhinoviruses that cause respiratory infections. The gene discussed is RNF19B; the disease is infection.