With the current evidence that the Kv7.2 channel plays a role in neurodevelopment and that variants in KCNQ2 are enriched in ASD cohorts, the KCNQ2 KO model was also subjected to extensive behavioral analysis; an in-depth behavioral study, indeed, recently showed autism-associated behaviors such as a decrease in social behavior and enhanced repetitive behaviors in KCNQ2 heterozygous KO mice (Kim et al., 2020). The gene discussed is KCNQ2; the disease is autism.