However, if this proves to be the case, this could open a whole new level of complexity to KCNQ2-related disorders, as astrocytes are known to contribute to the maintenance and formation of neuronal circuits and are known to play a role in the pathogenesis of several neurodevelopmental disorders, including ASD, Rett syndrome, and Fragile X (Molofsky et al., 2012; Sloan and Barres, 2014; Petrelli et al., 2016). This evidence concerns the gene KCNQ2 and neurodevelopmental disorder.