Inhibits neuraminidase activity, restrain influenza A (H1N1) virus, reduce the lung index of infected mice and ameliorates the lung pathological changes, suppresses the viral infection‐induced up‐regulation of TLR7 signaling pathway, such as TLR7, MyD88, and NF-κB (p65), at both the mRNA and protein levels, and inhibits the viral infection‐induced increase in Th1/Th2 and Th17/Treg ratios as well as the production of inflammatory cytokines. Here, TLR7 is linked to viral infectious disease.