The number of infiltrated neutrophils in the colonic mucosa of IL-4Rα-/- colitis mice was dramatically reduced compared to that in WT colitis mice (Figures 3A,B; 169.9 ± 24.5 in WT colitis, 78.9 ± 11.7 in IL-4Rα-/- colitis; p < 0.001). Here, IL4R is linked to colitis.