Established associations between these genes and HA include GSN and familial amyloidosis of the Finnish type (FAF; Nikoskinen et al., 2015), TTR and transthyretin-related amyloidosis (AMYL-TTR; Sekijima, 2015), ITM2B and familial British dementia or familial Danish dementia (Del Campo and Teunissen, 2014), as well as CST3 and cerebral amyloid angiopathy (Abrahamson et al., 1989). Here, ITM2B is linked to ITM2B amyloidosis.