It would additionally be interesting to see if other behaviors that are induced by stimuli that increase CCL2 and have also been shown to be affected by loss or antagonism of CCR2 such as stress-induced anxiety (Wohleb et al., 2013) and methamphetamine conditioned place preference (Wakida et al., 2014), would also be blocked by this HSV vector. The gene discussed is CCL2; the disease is Anxiety.