Immunohistochemical studies carried out on post-mortem brains of AD and LBD patients reported an increase in the number of astrocytes double-labeled with α7nAChR and GFAP antibodies, in most areas of the hippocampus and entorhinal cortex in AD, but not in LBD (Teaktong et al., 2003, 2004). The gene discussed is CHRNA7; the disease is Alzheimer disease.