CD40LG and myeloid sarcoma: However, only the CSF IgM levels reached statistical significance in MS patients when compared to controls (fold change = 1.46, p = 0.013; Figure 1B), while there was no difference in IgG (fold change = 0.96, p = 0.360; Figure 1C) and IgA (fold change = 0.27, p = 0.700; Figure 1D) levels between the two groups.