In a previous study, we have shown that DNA methylation regulated potential gene networks, pathophysiological pathways including PDGFR, EGFR, NTRK3(RTKs) as well as mTOR signaling and several other potential epilepsy-related genes associated with FCD type II (Dixit et al., 2018). Here, EGFR is linked to isolated focal cortical dysplasia type II.