CTBP1 and glioblastoma: We note that the transcriptional patterns of iPSC-derived patient cell models is somewhat different from that of a reconstituted exogenously introduced CTBP1p.R342W mutant allele (Beck et al., 2019), suggesting that the cell type (glioblastoma vs primary neuron) and/or the endogenous chromatin context influence the gene expression of the CTBP1 mutant allele.