SLC11A2 and age-related macular degeneration: Studies confirm alterations in iron homeostasis and increased iron accumulation in AMD retinas, which contribute to the excess ROS formation catalyzed by Fe3+ ions, increased expression of the Divalent metal transporter 1 (DMT 1) and the decrease of Ferroportin 1 (FPN 1) gene expressions (Blasiak et al., 2011[8]).