When testing for enriched terms in these 25 genes, biological processes related to apoptosis, such as regulation of apoptotic process and programmed cell death were at the top of the list (Supplementary file 1) and included, among others, genes such as Fosb and Mitf that have been connected with AD (Solé-Domènech et al., 2016; Gupta et al., 1986). The gene discussed is MITF; the disease is Alzheimer disease.