Recent studies of cGAS-STING signaling in insects have demonstrated that Drosophila STING drives NF-κB and autophagy signaling to restrict viral infection (Goto et al., 2018; Gui et al., 2019; Hua et al., 2018; Liu et al., 2018b; Martin et al., 2018). The gene discussed is NFKB1; the disease is viral infectious disease.