We further identified 10 core genes (AGR2, FXYD3, B3GNT3, MISP, TSPAN1, PKP3, CBLC, MUC13, S100P, and TMEM45B) that were up-regulated in PCC tissues relative to healthy controls based on MCC evaluation results. The gene discussed is B3GNT3; the disease is Merkel cell skin cancer.