A large network of 29 genes, included the two of the RV-responsive gene-chromatin pairs (PSMB8 and PRKCQ) (Supplementary Table 3), four genes (out of 14 RV-responsive genes in this region) at the most statistically significant childhood onset asthma locus on 17q12 (ERBB2, PSMD3, CDK12, SMARCE1), four genes out of nine RV-response genes at two 5q31.1 loci (CSF2, IRF1, KIF3A, AFF4), and 15 HLA region genes (out of 39 RV-responsive genes in this region). This evidence concerns the gene IRF1 and asthma.