IL-37 prevented the development of the inflammatory milieu we observed in WT NEC pups: Expression of the pro-inflammatory genes Il6, Il1b, Cxcl1, and Il36g, but not Il36b, was similar to the dam-fed baseline in IL-37tg NEC mice (Fig. 3a-c, Supplementary Fig. 3a). This evidence concerns the gene IL1B and necrotizing enterocolitis.