Compared with si-NC+NC, si-PVT1 co-transfected miR-194-5p mimics could accelerate the ratio of the relative apoptosis about 10.44 times in T24 (P<0.001) and about 9.91 times in UM-UC-3 (P<0.001), what’s more, miR-194-5p inhibitor could partially reverse promoting apoptosis on BC cells migration induced by si-PVT1 and reduced about 255.36% in T24 and about 277.04% in UM-UC-3 (Figure 5G, 5H). This evidence concerns the gene PVT1 and breast cancer.