CASP1 and neoplasm: Instead, tumor burden of NMU-treated wild type mice that received caspase-11 ko bone marrow cells had higher tumor lesions than NMU-treated caspase-11 ko mice that received wild type bone marrow cells, strengthening what already observed for TAMs which use caspase-11/caspase-1/NLRP3 axis to promote lung tumorigenesis [11].