There were no significant differences between the groups in terms of sex, age, duration of diabetes, BMI, LDL-c level, HDL-c level, HOMA-IR level, fasting plasma glucose level, fasting C-peptide level, fasting serum insulin level, hemoglobin A1c percentage, percentage of current smokers and use of sulfonylurea (all P > 0.05). This evidence concerns the gene INS and diabetes mellitus.