The study data led to a significant concordance of the increase in the average circulating level of Lp-PLA2 with that of its incidence, especially for men, which is why we postulate not only that the enzyme can be supported as a biomarker in chronic ischaemic heart disease, but also that it manifests specificity in relation to the patient’s sex. The gene discussed is PLA2G7; the disease is coronary artery disorder.