OPA1 and autosomal dominant optic atrophy: Genetic disorders of mitochondrial dynamics comprise defects of mitochondrial fusion triggered by mutations in MFN2 or OPA1, exhibiting as Charcot–Marie–Tooth type 2A and autosomal dominant optic atrophy, respectively [288,289,290], and impaired mitochondrial fission caused by mutations in DRP1 [291] and MFF [292].