FREM2 and glioblastoma: Candidate miRNAs were selected based on their target genes, vimentin (VIM), nucleolin (NCL), nucleosome assembly protein-1 like-1 (NAP1L1), FRAS1-related extracellular matrix protein 2 (FREM2), and sprouty RTK signaling antagonist 1 (SPRY1) [6,19,20,21], which were previously associated with GBM in our studies.