A study on scleritis carried out in 446 Asian patients and 710 healthy controls associated both the CTLA-4 rs3087243-GG genotype (OR = 1.55; CI95% = 1.19–2.01) and the CTLA-4 rs3087243-G allele (OR = 1.46; CI95% = 1.18–1.85) with a higher risk of developing the disease, compared with healthy controls [28]. Here, CTLA4 is linked to scleritis.