CTLA4 and rheumatoid arthritis: In this conceptual framework, our objective is to assess the role of SNPs of these three genes, CTLA-4 (rs3087243, rs231775 and rs5742909), CD80 (rs57271503) and CD86 (rs1129055), as possible response predictors (EULAR response, LDA and remission) in patients with RA treated with ABA.