The only protein unique in DS cases is actin-related protein 2/3 complex subunit, while the proteins over-expressed in DS are: Cofilin-1, 2, Tropomyosin alpha and beta chain, Tubulin alpha and beta with different isoforms, Myosin-9, Ezrin, and Profilin-1. This evidence concerns the gene ACTR2 and Dravet syndrome.