Twenty-three of these 60 tumors expressed transcripts encoding at least one of the α subunits, most commonly GABRA3 or GABRA5. Of tumors expressing GABRA3 or GABRA5 transcripts, all expressed both GABRD and GABRE, while over half also expressed GABRG1. These findings suggested that some ACC tumors contain multiple subtypes of GABAA receptors. Here, GABRD is linked to adrenal cortex carcinoma.