A frameshift variant (c.1041dup, p.(Ser348Glnfs*2)) was identified in the deafness gene CDC14A (NM_033312.2, DFNB32) in affected family members of family 6 (IV.1, IV.2) and co-segregated with HL in this family (Figure 1). The gene discussed is CDC14A; the disease is Hodgkins lymphoma.