SKP2 and cancer: In accordance with these recent data, we found in this study that genetic depletion of Fasn resulted in the lower growth rate of c-Myc/MCL1/Cre tumors as well as in the decrease of Cdk1, Cdk2, Skp2, and Survivin/Birc5 genes, which have been previously found to be regulated by FASN in cancer cells [31].