Future work is needed to build on the current studies’ results to investigate further on inflammatory variables such as C-reactive protein since it was proposed as a component of MetS, Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) can be added on the model as a measure of insulin resistance [35] and lastly optimal cut-points of the obesity indices using Receiver operating characteristic (ROC) can be determined. The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.