Subsequently, DEGs of the turquoise module were displayed in the global regulatory network to identify the intersection pathways of PRKCB, which supported the pleiotropic roles of PRKCB in AD pathophysiology responsible for gap junction [18], FcγR-mediated phagocytosis [31], MAPK and VEGF signaling pathways [16, 38]. The gene discussed is FCGR2A; the disease is Alzheimer disease.