Furthermore, we found that the ten signaling pathways significantly correlated with these genes were focal adhesion, the mTOR signaling pathway, the HIF-1 signaling pathway, the PI3K-Akt signaling pathway, the ErbB signaling pathway, chronic myeloid leukaemia, pathways in cancer, glyoxylate and dicarboxylate metabolism, glycosaminoglycan degradation, and the insulin signaling pathway (Figure 9). The gene discussed is AKT1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.