The case of carcinoma growth regulation by Gal-1, which is started by lattice formation with α5β1-integrin that is switched on/off by regulating extent of α2,6-sialylation of the glycoprotein’s N-glycans, offers a precedent, in which expression of galectin and counterreceptor are intimately orchestrated [37]. This evidence concerns the gene GAL and carcinoma.