IFNL3 and cryohydrocytosis: Given that sex, HOMA-IR, TC, hemoglobin and IFNL3-rs12979860 genotype were HCV-related factors associated with serum ferritin levels, special caution is demanded in male CHC patients with high HOMA-IR and TC but low Hb levels and an IFNL3-rs12979860 non-CC genotype due to the potential poor prognosis linked with high ferritin levels.