UBE2F and neoplasm: However, the tumor sizes in nude mice injected with cells UBE2F KO were significantly smaller than these from mice injected WT cells under chemotherapy condition (upon cisplatin or carboplatin injection) (tumor size at 21 days: cisplatin, 44.2 vs. 71.3 mm2 for UBE2F KO vs. WT, P < 0.0001; carboplatin, 46.4 vs. 74.7 mm2 for UBE2F KO vs. WT, P < 0.0001) (Fig. 6A).