IFNG and hepatocellular carcinoma: In addition, exosomes derived from α-fetoprotein (AFP)-expressing DCs stimulated mice with hepatocellular carcinoma to produce more IFN-γ-expressing CD8+ T cells, with increased IFN-γ and IL-2 and reduced CD25+Foxp3+Tregs, IL-10 and TGF-β [63].