In the NSCLC dataset, when the expression of MAP4K4-TP53 interaction (“EXP_MAP4K4_X_EXP_TP53”) increases, the average \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\hbox {IC}_{50}$$\end{document}IC50 is slightly decreased (Pearson correlation = − 0.10). The gene discussed is TP53; the disease is non-small cell lung carcinoma.