CFTR and cystic fibrosis: The North-American and European recommendations were as follows: (i) to start CFTR modulators as soon as possible, to reduce pulmonary exacerbations and hospitalizations; (ii) to practice telemedicine as much as possible; (iii) to reinforce adherence to already prescribed regimens; (iv) to promptly and aggressively treat CF exacerbations to prevent avoidable hospitalizations; and (v) to continue to communicate with the patients by emails, phone calls, etc. [18,19].